[Dutchie80]

Thanks BDT- your help is greatly appreciated

It's soo frustrating that no one thinks that ANA contributes to implantation failure but I certainly do. I have read a lot about it and I'm convinced they are problematic for implantation as well as pg. Dr Beer's book defines ANA as a category 3 immune problem where these antibodies first form in the blood and later graduate to the lymphatic system and tissue. After repeated losses, antibodies to DNA components can develop into antibodies that occupy organs such as the uterus, and cause local inflammation that may contribute to further m/c. Dr Beers uses IVIG for patients with ANA but I've read of a lot of women using prednisone and some using heparin/clexane. I've fortunately never had a m/c and have even achieved a natural pg about 11 yrs ago that didn't end in m/c, perhaps this is why no one thinks it contributing to implantation failure for me.

It's just soo damn confusing and I'm no doctor but I am going to keep 'bugging' my FS about it. I think I'm just going to go with the aspirin this cycle as my rheumatologist said there's some newer research out thats shows that ANA may benefit from aspirin, he also said if aspirin works for some antibodies (APA for example) then why couldn't they work for ANA.

So I'm going to begin aspirin 24-48hrs after ET. I don't know if this is enough but I'm content with just aspirin just for this cycle. I suppose I want to see if it will work with just aspirin.

My ANA titer was 1:320, I don't know what my most recent titer was, I stupidly forgot to ask though he did say that it was quite high so I'm assuming it was higher than 1:320.