Hi all, I am new to this site and have a question about Puregon. I am currently going through ovulation induction due to polycystic ovary syndrome. Currently on our Fifth try. The first try I took 50units and ended up producing 4 eggs, which is obviously not good for a natural cycle. Next 2 cycles I was on 33 and 1/3 units and both times produced beautiful single eggs, but did not full pregnant. The fourth cycle all of a sudden the 33 and 1/3 did not stimuate my ovaries enough and I had to go up to the next dosage which I believe is about 44 units. Again this stimuated one egg but did not result in pregnancy. This cycle I have been on the 44 units and even with the Dr extending the period of time on this dose, it has not stimuated my follies enough. So now I am going to be back on 50 units for 3 days and then have another scan to check what is going on.
My rather long winded question is, is this normal??? Can your body become almost a little resistant to the puregon? It just seems that in the beginning I was almost hyper sensitive to it and now, it is getting harder and harder for it to work.
